Tuesday, January 31, 2012

Ed Gillespie hatches plan to replace lousy campaign websites (Daily Caller)

Veteran Republican strategist Ed Gillespie?s latest plan to help GOP candidates win state-level elections involves making sure they aren?t stuck with crappy campaign websites.

Gillespie?s organization, the Republican State Leadership Committee, has made a six-figure investment in an initiative that promises to replace poorly designed candidate websites with sophisticated, yet inexpensive sites.

The average budget for a state senate campaign is only $190,000, said RSLC press secretary Adam Temple. But a complete website created by the group?s GOPro program only costs Republican candidates $550.

?They can?t afford to use a major DC firm, and a lot of times they end up using local yokels who end up charging them two or three times that,? said Michael Luethe, a political consultant in North Carolina who has run four campaigns using the program.

?Candidates really are stuck in a difficult position between having to choose a crappy website or something that looks professional,? he told The Daily Caller. ?And usually professional ones are cost-prohibitive.?

The Daily Caller got a sneak peak at how the program works: Republican state legislative candidates who want to design a campaign website pay the $550 fee, fill out some information and choose from among five website templates.

Some sites have been launched in as little as 15 minutes, Temple said. The project, he said, is quick and easy to set up, is relatively inexpensive, and simplifies raising money online.

Temple said Democrat-leaning groups have done similar things, but not ?to the degree? of GOPro.

It?s available for Republican state-legislature candidates only, he said. The RSLC makes sure candidates are Republicans before approving their participation.

Fifteen candidates have used the program in Louisiana, Mississippi and North Carolina.

Rob Bryan, who is running for the state house in Charlotte, N.C., used the program to create FriendsofRob.com.

?I?ve seen a lot more expensive [websites] that I?ve liked less,? he told TheDC.

?I?ve gotten loads of compliments,? Bryan said. ?People love the site, think it looks great. ? It?s easy for people to give [money], it?s easy for us to track.?

Temple said the RSLC hopes several hundred candidates will use it in 2012. The group plans an nationwide rollout of the program in early February.

The RSLC?s mission is to elect more Republicans to the down-the-ballot offices of attorney general, lieutenant governor, secretary of state and legislator ? and to build ?the farm team? of future Republican candidates for higher office.

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Source: http://us.rd.yahoo.com/dailynews/rss/gop/*http%3A//news.yahoo.com/s/dailycaller/20120129/pl_dailycaller/edgillespiehatchesplantoreplacelousycampaignwebsites

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Saturday, January 28, 2012

Army chief lays out Army cuts in Europe (AP)

WASHINGTON ? Gen. Raymond Odierno (oh-dee-EHR'-noh), the Army chief of staff, says the Pentagon will take two heavy armor brigades out of Europe in 2013 and 2014 and eliminate them.

Odierno says the military is working hard to mitigate the impact on European allies, and will rotate other Army units into the region to train with NATO partners.

The units will be eliminated, rather than moved back to the United States. Odierno says removing two of four brigades now in Europe will not necessarily make NATO allies shoulder more of the load if ground forces are needed for a large-scale operation in the region.

The units to be dismantled are based in Germany ? the 172nd Infantry Brigade, currently in Grafenwoehr, and the 170th Infantry Brigade in Baumholder.

THIS IS A BREAKING NEWS UPDATE. Check back soon for further information. AP's earlier story is below.

The Pentagon's decision to cut the size of the Army by 80,000 soldiers will force the military to rely more on the National Guard and reserves, particularly if the U.S. gets into two major, long-term combat operations at the same time, according to the top Army officer.

Gen. Raymond Odierno, chief of staff of the Army, said he is comfortable with the mandate to go from 570,000 soldiers during the height of the Iraq war to 490,000 by 2017. But he suggested that the U.S. will now have to keep its reserve forces at a higher level of readiness than it did before the wars in Iraq and Afghanistan pressed tens of thousands citizen soldiers into service to buttress the active duty Army.

He also said his support for the force cuts hinges on the fact that the Army will have five more years to make the reductions, largely through normal attrition. He acknowledged, however, that a small number of officers may have to be forced to leave.

As the Iraq war dragged on, the Pentagon had to recruit thousands of additional active duty soldiers and beef up and repeatedly tap reserve brigades in order to meet the combat demands there and in Afghanistan. For roughly eight years, the U.S. battled in both countries at the same time, stretching and straining the Army nearly to the point of breaking.

Meeting that type of commitment with an Army of 490,000 would not work, Odierno said.

"Do I have the capability to go into Korea and meet the requirements, yes," he said, when asked about the risks of a smaller force. "Do I have the ability to stay there for 10 years? No."

If the military had to fight two large, simultaneous, long-term wars, he said, the U.S. would rely more heavily on its allies in the region and call for a massive mobilization of the reserves.

"Because of the fact that they (Guard and reserves) have been involved in combat operations for very long period of time, we are going to come up with a readiness model that will keep them at a little bit higher level than they have been in the past," Odierno told reporters during an interview in his Pentagon office. And if needed, he said, the U.S. would use reserves to "buy us time to increase the active component" to wage two large, intensive wars.

A battle-hardened leader who commanded troops during three tours in Iraq ? including as top commander there from 2008 to 2010 ? Odierno has taken on a broad restructuring of the Army in order to save money while retaining the fighting capabilities needed to go to war.

Over the long-term, U.S. officials said they are planning to slash the number of combat brigades from 45 to possibly as low as 32. The officials spoke on condition of anonymity to discuss planning. Odierno said eight brigades will be shelved over the next several years, and officials will decide in the next six months or so if additional units should go.

Officials said the changes will likely increase the size of each combat brigade ? generally by adding another battalion ? in a long-term effort to ensure that those remaining brigades are robust and able to perform their missions without straining the force.

A brigade is usually about 3,500 soldiers but can be as large as 5,000 for the heavily armored units. A battalion is usually between 600 and 800 soldiers.

"We will make our brigades more capable to operate across missions, will eliminate unnecessary overhead, and allow us to sustain more combat capability if we do this right," said Odierno, who did not provide any details about the restructuring.

Odierno also stressed that the new defense strategy calling for a greater focus on the Asia Pacific region does not mean that the Army will become less relevant. He said that while some may think it means the U.S. will rely more on the Air Force and Navy, it actually will require the Army to play a major role.

He said the new defense strategy, laid out by President Barack Obama earlier this month, calls for increased military capabilities in countering terrorism, fighting irregular warfare, defeating and deterring aggression, and countering weapons of mass destruction ? all missions that require Army capabilities.

Both Odierno and Defense Secretary Leon Panetta have made it clear that the military as a whole must cut back its payroll and health care expenses while still giving troops and their families the support they need.

Source: http://us.rd.yahoo.com/dailynews/rss/usmilitary/*http%3A//news.yahoo.com/s/ap/20120127/ap_on_go_ca_st_pe/us_army_cuts

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Too Few Americans Getting Screened for Common Cancers: CDC (HealthDay)

THURSDAY, Jan. 26 (HealthDay News) -- The number of Americans being screened for colon, breast and cervical cancers still fall below national targets, federal health officials said Thursday.

In 2010, 72.4 percent of women were being screened for breast cancer, below the target of 81 percent, for cervical cancer it was 83 percent of women, while the target is 93 percent, and for colon cancer 58.6 percent of Americans were screened, missing the target of 70.5 percent, according to the U.S. Centers for Disease Control and Prevention.

"Not all Americans are getting the recommended screening for breast, cervical and colorectal cancer," said report co-author Mary C. White, branch chief of the CDC's Division of Cancer Prevention and Control. "There continue to be disparities for certain populations."

The screening rates are particularly low among Asians and Hispanics, according to the report in the Jan. 27 issue of Morbidity and Mortality Weekly Report.

Among Asians, the screening rate for breast cancer was 64.1 percent, for cervical cancer it was 75.4 percent, and for colon cancer it was 46.9 percent.

Hispanics were less likely than non-Hispanics to have screening for cervical and colon cancer (78.7 percent and 46.5 percent, respectively), the researchers found.

Screening is important, said Dr. Stephanie Bernik, chief of surgical oncology at Lenox Hill Hospital in New York City.

"Screening saves lives," she said. "When you catch a cancer at a smaller size it does affect outcome."

Some people may be confused about screening, because different medical groups have different screening protocols, Bernik said.

"It's hard to get people to do screening in general. People look for any excuse not to get screened. When they see there is a controversy about when to start screening, they look at it as an opportunity to not do the test," she said.

Bernik also admits that screening can result in some over-treatment.

"With screening comes that risk," she said. "Unfortunately, we are not at a point where we can select the patients that are not going to have a problem, so we treat everyone equally. So, there is a little bit of over-treatment but, overall, you are improving survival for many people."

The U.S. Preventive Services Task Force recommends that women aged 50 to 74 get a mammogram every two years to screen for breast cancer.

Women aged 21 to 65, or those who have been sexually active for three years, should have a Pap test to screen for cervical cancer at least every three years, the task force recommends.

For colorectal cancer, men and women aged 50 to 75 should be screened with a yearly fecal occult blood test or sigmoidoscopy every five years, or have a colonoscopy every 10 years.

Other highlights of the report include:

  • Breast cancer screening rates remained stable from 2000-2010, varying only about 3 percent.
  • Colon cancer screening rates increased from 2000-2010, to more than 58 percent for both men and women.
  • Cervical cancer screening rates dipped 3.3 percent from 2000-2010.
  • Screening rates for all these cancers was much lower among the uninsured or those who didn't have a regular doctor.

The Affordable Care Act is expected to lower these barriers to access by expanding insurance coverage, the authors said.

"Other efforts are needed, such as developing systems that identify persons eligible for cancer screening tests, actively encouraging the use of screening tests, and monitoring participation to improve screening rates," the authors added.

More information

For more on cancer screening, visit the U.S. Centers for Disease Control and Prevention.

Source: http://us.rd.yahoo.com/dailynews/rss/health/*http%3A//news.yahoo.com/s/hsn/20120127/hl_hsn/toofewamericansgettingscreenedforcommoncancerscdc

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Friday, January 27, 2012

'I Just Want My Pants Back' Cast Calls 'Jersey Shore' 'A Great Show'

'Pants Back' cast throws a party in Brooklyn to celebrate the show's much-anticipated premiere on February 2.
By Jocelyn Vena


Peter Vack and Kim Shaw
Photo: MTV News

NEW YORK — On Thursday night, the cast of MTV's latest scripted comedy, "I Just Want My Pants Back," gathered at the Public Assembly in Brooklyn, where they not only celebrated the show's imminent arrival, but also got to hang out with their Thursday night cohorts, the cast of the "Jersey Shore."

The pilot for the series originally got some love when it made its debut after the VMAs in August, and now it will officially kick off its run next Thursday. The cast, it seems, can't wait to finally have it on air.

"At last! I know everyone's been asking," Jordan Carlos joked to MTV News about the long-simmering delay. "My parents can finally get off my back; it's real. It'll be on on Groundhog Day, which happens to be my birthday as well."

"We've been seeing the commercials for the show for years now," Sunkrish Bala teased. "Slow burn, but it's all coming to a beautiful conclusion right now."

"It feels so crazy to be here right now," co-star Kim Shaw said. "We wanted people to see it at the VMAs to give people a taste of what we were filming, and now that we're finished with the series, we're so excited that everyone gets to see the whole thing."

Having already had one very high-profile premiere, it seems that next week it will get one more thanks to the "Jersey Shore" as its lead-in. "It's awesome," Elisabeth Hower said. "The fact that the network has so much confidence around us really means a lot, and I think that says a lot about the show. Please watch the show. We're nice people."

"It's an amazing lead-in," said Peter Vack, leading man of "Pants Back." " 'Jersey Shore' is a great show."

While "Jersey Shore" and "Pants Back" may seem like different shows on the surface — one's scripted, one's a reality show; one's about hipsters, one's about guidos — they both deal with a group of friends navigating their love lives. "Pants Back" follows a group of twentysomethings in New York City as they pilot love, friendship and the job market with a good dose of dirty humor and some heart thrown in for good measure.

"The show just goes so many fun places," Vack teased. "It's just a crazy ride, and I'm excited for people to take the ride with us."

"Pants Back" premieres on February 2 at 11 P.M. ET/PT right after "Jersey Shore."

Are you excited for "I Just Want My Pants Back"? Let us know in the comments section!

For more on "I Just Want My Pants Back," be sure to check in with MTV's Remote Control blog.

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Source: http://www.mtv.com/news/articles/1678020/i-just-want-my-pants-back-premiere-party.jhtml

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Thursday, January 26, 2012

'Open for business': Ind. House OKs right-to-work (AP)

INDIANAPOLIS ? Indiana is poised to become the first right-to-work state in more than a decade after the Republican-controlled House passed legislation on Wednesday banning unions from collecting mandatory fees from workers.

It is yet another blow to organized labor in the heavily unionized Midwest, which is home to many of the country's manufacturing jobs. Wisconsin last year stripped unions of collective bargaining rights.

The vote came after weeks of protest by minority Democrats who tried various tactics to stop the bill. They refused to show up to debate despite the threat of fines that totaled $1,000 per day and introduced dozens of amendments aimed at delaying a vote. But conceding their tactics could not last forever because they were outnumbered, they finally agreed to allow the vote to take place.

The House voted 54-44 Wednesday to make Indiana the nation's 23rd right-to-work state. The measure is expected to face little opposition in Indiana's Republican-controlled Senate and could reach Republican Gov. Mitch Daniels' desk shortly before the Feb. 5 Super Bowl in Indianapolis.

"This announces especially in the Rust Belt, that we are open for business here," Republican House Speaker Brian Bosma said of the right-to-work proposal that would ban unions from collecting mandatory representation fees from workers.

Republicans recently attempted similar anti-union measures in other Rust-Belt states like Wisconsin and Ohio where they have faced massive backlash. Ohio voters overturned Gov. John Kasich's labor measures last November and union activists delivered roughly 1 million petitions last week in an effort to recall Wisconsin Gov. Scott Walker.

Indiana would mark the first win in 10 years for national right-to-work advocates who have pushed unsuccessfully for the measure in other states following a Republican sweep of statehouses in 2010. But few right-work states boast Indiana's union clout, borne of a long manufacturing legacy.

Oklahoma, with its rural-based economy that produces comparatively fewer union jobs than Indiana, passed right-to-work legislation in 2001.

Hundreds of union protesters packed the halls of the Statehouse again Wednesday, chanting "Kill the Bill!" and cheering Democrats who had stalled the measure since the start of the year.

House Minority Leader Patrick Bauer said the legislative battle has been an "unusual fight" from the beginning, but Democrats waged a noble effort against majority Republicans determined to pass the bill.

"What did they fight for? They fought for less pay, less workplace safety and less health care. This is their only job plank: job creation for less pay with the so-called right to work for less bill."

Republicans foreshadowed their strong showing Monday when they shot down a series of Democratic amendments to the measure in strict party-line votes. Democrats boycotted again for an eighth day

Republicans handily outnumber Democrats in the House 60-40, but Democrats have just enough members to deny the Republicans the 67 votes needed to achieve a quorum and conduct any business. Bosma began fining boycotting Democrats $1,000 a day last week, but a Marion County judge has blocked the collection of those fines.

The measure now moves to the Indiana Senate which approved its own right-to-work measure earlier in the week. Gov. Mitch Daniels has campaigned extensively for the bill and said he would sign it into law.

___

Tom LoBianco can be reached at http://www.twitter.com/tomlobianco

Source: http://us.rd.yahoo.com/dailynews/rss/democrats/*http%3A//news.yahoo.com/s/ap/20120125/ap_on_re_us/us_indiana_right_to_work

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Stocks erase losses on Fed promise of low rates (AP)

Stocks turned mixed Wednesday afternoon, erasing earlier losses, after the Federal Reserve said it will keep interest rates near zero for much longer than it had previously announced. Demand for ultra-safe Treasurys soared, pushing bond yields lower.

The Fed's monetary policy committee said it is unlikely to raise interest rates before 2014, extending a period of record-low rates by more than a year. Lower interest rates can encourage investment in stocks by reducing traders' returns from bonds.

The Fed plans to keep interest rates very low in part to make loans more affordable for people and companies. Access to credit is vital for the economic recovery.

The Dow Jones industrial average and Standard & Poor's 500 index both turned slightly positive shortly after the Fed's 12:30 p.m. Eastern announcement. Both had been solidly negative all morning; the Dow had lost as many as 95 points.

The yield on the 10-year Treasury note plunged to 1.98 percent from 2.05 percent an hour before the Fed announcement. Bond yields fall when demand for them increases.

Markets had opened mostly lower on fears about Greece's slow progress in talks with bondholders about reducing the nation's crushing debt load.

Tech stocks rose, bucking the wider market, after consumer electronics giant Apple Inc. reported a best-ever quarter driven by strong sales of iPhones and iPads.

Apple's stock jumped 6.2 percent, helping lift the Nasdaq composite index by 16 points, or 0.6 percent, to 2,802. The Nasdaq is up 7.6 percent this year, more than twice the gain for the Dow Jones industrial average.

The Dow was down 19 points, or 0.2 percent, at 12,657. The S&P 500 index fell a fraction to 1,313.

The declines follow a two-month surge that lifted the broad S&P 500 index by 13 percent since its recent low on Nov. 25. As fears recede about the European debt crisis, big-time investors such as hedge funds will be drawn back into the market, fueling more gains, said Joe Bell, senior Equity Strategist at Schaeffer's Investment Research.

After such a strong rally, "we could see a ... slight pullback or consolidation; but overall we're bullish," Bell said.

Later Wednesday, Fed Chairman Ben Bernanke will take questions from reporters in his quarterly news conference.

European markets mostly closed lower as Greece's bondholders held a closed-door meeting to discuss whether they will continue to negotiate with the crisis-stricken nation.

Greece wants the investors, mostly banks and hedge funds, to voluntarily write off about half of its debt. Otherwise, Greece will be unable to obtain needed bailout cash and will default. That could set off a financial crisis similar to the aftermath of Lehman Bros.' failure in 2008.

Benchmark stock indexes in Italy and London closed a half-percent lower. Borrowing costs for Italy and France increased, a sign of traders' fears that the debt crisis will spread. Adding to the gloom was a report that Britain's economy shrank by 0.2 percent in the fourth quarter.

With Apple's gains Wednesday, the Cupertino, Calif. electronics maker again surpassed Exxon Mobil Corp. as the company with the biggest market value. Apple said late Tuesday that it sold 37 million iPhones in its fiscal first quarter, the first period after the death of CEO and co-founder Steve Jobs. That was coupled with a big jump in iPad sales to 15.4 million, and a more modest increase in Mac sales.

Apple's net income leapt 118 percent from the same quarter a year earlier. Revenue soared 73 percent. Both results blew the doors off Wall Street's expectations.

Among the other companies making big moves after announcing earnings:

? US Airways Group Inc. jumped 18 percent and Delta Air Lines Inc. rose 6.6 percent. Both carriers reported earnings that were far better than Wall Street analysts expected. The airlines raised fares during the fourth quarter while keeping costs under control. Delta also cut the number of flights it makes to keep pace with demand.

? WellPoint Inc., the nation's largest health care insurer based on enrollment, fell 4.9 percent. The company's fourth-quarter earnings dropped 39 percent, far more than analysts had expected. The Indianapolis company's full-year forecast also fell short of Wall Street's forecasts. Medical claims, its largest expense, rose nearly 10 percent in the quarter.

___

Follow Daniel Wagner at http://www.twitter.com/wagnerreports.

Source: http://us.rd.yahoo.com/dailynews/rss/stocks/*http%3A//news.yahoo.com/s/ap/20120125/ap_on_bi_st_ma_re/us_wall_street

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Wednesday, January 25, 2012

IRL: the Kindle Touch, a repurposed Army bag and a non-user replaceable laptop battery

Welcome to IRL, an ongoing feature where we talk about the gadgets, apps and toys we're using in real life and take a second look at products that already got the formal review treatment.

Hi there, folks. It's that time of the week where we share our close and very personal experiences with various gadget paraphernalia. This week, Brian makes the switch from the Nook Simple Touch to the Kindle Touch, Ben explains why he'd rather replace his own laptop battery, thank you very much, and Don makes the case for a laptop bag that looks anything but.

Continue reading IRL: the Kindle Touch, a repurposed Army bag and a non-user replaceable laptop battery

IRL: the Kindle Touch, a repurposed Army bag and a non-user replaceable laptop battery originally appeared on Engadget on Wed, 25 Jan 2012 14:00:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/01/25/irl-the-79-kindle-a-repurposed-army-bag-and-a-non-user-replac/

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Long lines to bid farewell to Paterno (AP)

STATE COLLEGE, Pa. ? Decked out in Penn State hats and jackets, students and townspeople stood in a line more than a quarter-mile long Tuesday to pay their respects to Joe Paterno, the coach who for nearly a half century was the face of their university.

Mourners stood in a line along a main campus artery for the chance to file past Paterno's closed casket at the campus spiritual center during a 10-hour public viewing session.

They were preceded by Paterno family members ? the coach's son, Scott, was seen going in and out of the event ? and the Penn State football team, both present and past. Players wore dark suits and filed out of three blue Penn State buses, the same buses that once carried Paterno and the team to games at Beaver Stadium on fall Saturdays.

Among that group was Mike McQueary. As a graduate assistant to Paterno in 2002, he went to the coach saying he had witnessed former defensive coordinator Jerry Sandusky assaulting a boy in the shower at the Penn State football building. Paterno relayed that to his bosses ? including the head of campus police ? but university trustees felt he should have done more, and it played into their decision to fire the longtime coach on Nov. 9. That came four days after Sandusky was arrested on multiple child sex-abuse counts.

Dressed in a blue coat and tie with a white shirt, the school colors, McQueary was among thousands of expected mourners at an event that was to stretch late into Tuesday night.

One current and one former team member will stand guard over the casket for the duration of the public viewing, athletic department spokesman Jeff Nelson said.

"He left us too early and I think about the impact he could have made once he retired from coaching," Nelson said.

The 85-year-old Paterno, the winningest coach in major college football, died Sunday. The cause, lung cancer, was disclosed in November, just days after he was fired.

Earlier Tuesday, a line of ex-players stretched around the corner and down the block. Among the mourners were former Penn State and Pittsburgh Steelers great Franco Harris. Others there included NFL receivers Deon Butler and Jordan Norwood, Norwood's father and Baylor assistant coach Brian Norwood and former quarterback Daryll Clark.

The event marked the start of three days of public mourning as the Penn State community in State College and beyond said goodbye to the man who led the Nittany Lions to 409 wins over 46 years and raised the national profile of the school.

There is another public viewing Wednesday at Pasquerilla Spiritual Center, and after that Paterno's family will hold a private funeral and procession through State College.

On Thursday, the school's basketball arena will be the site of a public service called "A Memorial for Joe." Tickets were quickly snapped up for the event, even though there was a two-per-person limit for those ordering.

Former players began arriving shortly after members of Paterno's last team filed in. Some players hugged, and new Penn State coach Bill O'Brien shook hands with others at the curb outside the center.

Penn State linebacker Khairi Fortt recalled his coach's lessons.

"He said the most important thing for us was to keep the Penn State tradition going," the sophomore from Stamford, Conn., said after leaving the viewing.

Scott Paterno has said that despite the turmoil surrounding his termination from the school, Joe Paterno remained peaceful and upbeat in his final days and still loved Penn State.

Bitterness over Paterno's firing has turned up in many forms, from online postings to a rewritten newspaper headline placed next to Paterno's statue at the football stadium blaming the trustees for his death. A headline that read "FIRED" was crossed out and made to read, "Killed by Trustees." Lanny Davis, lawyer for the school's board, said threats have been made against the trustees.

Scott Paterno, however, stressed his father did not die with a broken heart and did not harbor resentment toward Penn State.

___

Associated Press writer Mark Scolforo contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20120124/ap_on_sp_co_ne/fbc_penn_state_paterno

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Tuesday, January 24, 2012

US aircraft carrier enters Gulf without incident

A U.S. aircraft carrier sailed through the Strait of Hormuz and into the Gulf without incident on Sunday, a day after Iran backed away from an earlier threat to take action if an American carrier returned to the strategic waterway.

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The carrier USS Abraham Lincoln completed a "regular and routine" passage through the strait, a critical gateway for the region's oil exports, "as previously scheduled and without incident," said Lieutenant Rebecca Rebarich, a spokeswoman for the U.S. Fifth Fleet.

The Lincoln, accompanied by strike group of warships, was the first U.S. aircraft carrier to enter the Gulf since late December and was on a routine rotation to replace the outgoing USS John C. Stennis.

The departure of the Stennis prompted Iranian army chief Ataollah Salehi to threaten action if the carrier passed back into the Gulf.

"I recommend and emphasize to the American carrier not to return to the Persian Gulf. ... We are not in the habit of warning more than once," he said.

The threat led to a round of escalating rhetoric between the two sides that spooked oil markets and raised the specter of a military confrontation between Iran and the United States.

Iran threatened to close the strait, the world's most important oil shipping gateway, while the United States warned such a move would require a response by Washington, which routinely patrols international sea lanes to ensure they remain open.

Iran appeared to ease away from its earlier warnings on Saturday, with Revolutionary Guard Corps Deputy Commander Hossein Salami telling the official IRNA news agency that the return of U.S. warships to the Gulf was routine and not an increase in its permanent presence in the region.

"U.S. warships and military forces have been in the Persian Gulf and the Middle East region for many years and their decision in relation to the dispatch of a new warship is not a new issue and it should be interpreted as part of their permanent presence," Salami said.

Pentagon officials declined to comment directly on Salami's remarks, but reiterated that continued U.S. presence in the region reflected the seriousness with which Washington takes its security commitments to partner nations in the region and to ensuring free flow of international commerce.

The Lincoln's arrival in the Gulf was unrelated to Iran's statement on Saturday.

Tensions between Iran and the United States have been escalating in recent weeks as President Barack Obama prepares to implement new U.S. sanctions against Iran over its nuclear enrichment program, which Tehran says is for energy production but the West believes is aimed at producing atomic weapons.

The EU is preparing to intensify sanctions against Tehran with an embargo on Iran's oil exports and possibly freezing the assets of Iran's central bank. Obama is preparing new U.S. sanctions that target foreign financial institutions that do business with Iran's central bank.

Both sides tried to scale down the rhetoric last week. The White House emphasized the United States was still open to international talks on Iran's nuclear program, even as it denied Iranian assertions that discussions were under way about resuming a dialogue.

The White House would not confirm or deny Iranian reports that Obama had sent a letter to Iranian leaders, but spokesman Jay Carney said any communications with Tehran would have reinforced the statements Washington has made publicly.

The United States supports talks between Iran and the so-called P5 + 1, the five permanent members of the U.N. Security Council -- Russia, China, France, England and the United States -- plus Germany.

Carney urged Iran to respond to the letter sent in October on behalf of the P5 +1 by European Union foreign policy chief Catherine Ashton.

"If the Iranians are serious about restarting talks, then they need to respond to that letter," Carney told a White House briefing. "That is the channel by which ... the restarting of those talks would take place."

Copyright 2012 Thomson Reuters. Click for restrictions.

Source: http://www.msnbc.msn.com/id/46093542/ns/world_news-mideast_n_africa/

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Stung by defeat, Romney ready to right tax "mistake" (Reuters)

Columbia, South Carolina (Reuters) ? Humbled by a stunning loss in South Carolina, Mitt Romney said on Sunday he would release this week the tax returns demanded by rivals as he bids to regain the upper hand in the volatile Republican presidential race.

Romney, the longtime front-runner in the Republican race and one of the wealthiest presidential candidates in history, lost to a resurgent Newt Gingrich in the conservative Southern state on Saturday after stumbling badly in debates with clumsy responses to demands that he disclose his tax history.

Trying to recapture his footing as the contest heads to more populous and more moderate Florida, Romney said he would release his 2010 returns and an estimate for 2011 on Tuesday.

"We made a mistake holding off as long as we did and it just was a distraction," Romney said on "Fox News Sunday."

Romney said the returns would be on the Internet and emphasized he was releasing two years of returns after Gingrich posted 2010 taxes on Thursday.

He slammed Gingrich as a Washington insider, a line of attack he is expected to use going forward, and called on his rival to release details of his contract with the government-sponsored mortgage finance giant Freddie Mac.

Gingrich's work for Freddie Mac could raise concerns for some voters in Florida, a state that has been hit hard by the downturn in the U.S. real estate market.

"He talks about great, bold movements and ideas, well what's he been doing for 15 years? He's been working as a lobbyist ... that's selling influence around Washington," Romney told about 300 supporters in a campaign stop later on Sunday outside Daytona Beach, Florida.

Romney's tax announcement was meant to draw a line under a bad week punctuated by his own missteps, a surprising turn in an otherwise tightly scripted campaign.

In the midst of a halting response to the tax return controversy, Romney said he paid a rate of about 15 percent, low compared with many U.S. wage earners but in line with what wealthy individuals pay on income from investments.

Gingrich, a former speaker of the House of Representatives with a sharp tongue that played well in debates, pounced on Romney's weak flank and walloped the former Massachusetts governor by 40 percent to 28 percent in South Carolina.

The Gingrich win reshaped the Republican race and reflected a party sharply divided over how to beat Democratic President Barack Obama in the November 6 election.

There have been three nominating contests so far and Gingrich, Romney and former Senator Rick Santorum have each won one.

A victory in Florida's primary on January 31 would restore Romney's luster after South Carolina, and a Gingrich win would solidify him as a serious challenger to the former business executive. A protracted and poisonous Republican battle, in turn, could be a boon to Obama's re-election bid.

"It's hard to see it ending soon. It could drag on to April," said Al Cardenas, the chairman of the American Conservative Union. Cardenas headed Romney's campaign in Florida in 2008, but has remained neutral this time.

"When this is over, we are going to have a presidential candidate showing all his warts. We are going to enter into a national election with a candidate whose chinks in the armor are visibly seen," he said.

With 19 million people, Florida presents logistical and financial challenges that may give an advantage to Romney's well-funded campaign machine.

In Florida, he leads Gingrich by 40.5 percent to 22 percent, according to polls cited by RealClearPolitics.com, conducted before Romney's battering in South Carolina. Santorum, a social conservative who won the Iowa contest but has struggled to gain traction since then, is third with 15 percent.

Texas Congressman Ron Paul, who is not campaigning in Florida, is fourth at about 9 percent.

ROMNEY FLOODS FLORIDA

Some Florida voters were delighted by Gingrich's rise.

Eugenio Perez, 58, a Miami property manager, said Gingrich's experience would help him in the White House.

"We live in a very complex world and we can't put a novice in such a high place, as we did in 2008," he said.

The more moderate electorate in Florida may help Romney, who has failed to consolidate conservative support despite his longtime front-runner status and had hoped to wrap up the nomination after Texas Governor Rick Perry and former Utah Governor Jon Huntsman bowed out last week.

Facing a real estate crisis and an unemployment rate of 9.9 percent, above the national average, Floridians are also expected to be more open to Romney's argument that he is the type of "CEO president" the country needs.

"I like the fact that Romney is a businessman who has been successful. Some people criticize that but I think that's commendable," said Mike Sullivan, 57, a professional golfer who attended the Romney rally.

"Right now, we need a chief executive who can run America like a business and not like the Salvation Army."

The tax release shift and financial advantage could help Romney regain his momentum after Gingrich's win.

A political action committee formed by Romney backers, Restore Our Future, has spent $5 million in Florida for Romney since mid-December, 20 times the amount spent there so far by any other group supporting a Republican candidate, according to Federal Election Commission filings analyzed by Reuters.

Romney could get some help from Santorum, who is competing with Gingrich to be the conservative alternative to Romney.

"It's a choice between a moderate and an erratic conservative - someone who on a lot of the major issues has been just wrong," Santorum told ABC's "This Week" program, saying Gingrich was out of step with many Republicans on Wall Street bailouts, health policy, immigration and global warming. "I think he's a very high-risk candidate.

Gingrich has see-sawed in national polls but has shown an uncanny ability to hang on, especially after an exodus of his staff last summer. Now he must prove he is the most "electable" choice despite hefty political and personal baggage.

Gingrich, who refers to Romney as a "Massachusetts moderate," said having his rival's taxes on the table would at least put an end to that part of the campaign narrative.

"As far as I'm concerned, that particular issue is now set aside and we can go on and talk about other bigger and more important things," Gingrich said on NBC's "Meet the Press."

But the tax issue will almost certainly not go away.

Income inequality has become a leading topic in the presidential race, and Obama has signaled he will talk about an economy that works "for everyone, not just a wealthy few" in his State of the Union address on Tuesday, the day of Romney's tax return release.

(Additional reporting by Ros Krasny in Coral Springs, Florida, Patricia Zengerle and David Adams in Miami, Terry Wade in Daytona Beach and David Morgan and Andrea Shalal-Esa in Washington. Writing by Jeff Mason and Patricia Zengerle; Editing by Mary Milliken and Peter Cooney)

Source: http://us.rd.yahoo.com/dailynews/rss/gop/*http%3A//news.yahoo.com/s/nm/20120123/ts_nm/us_usa_campaign

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Monday, January 23, 2012

EU online spending estimated to grow 16 percent, reach ?232 billion in 2012

Pardon us Americans as we act surprised, but it turns out that we have one more thing in common with our Euro brethren: a growing number of us dislike shopping in stores. According to Kelkoo estimates, online spending in the European Union is projected to continue its upward trend, which is said to reach somewhere in the neighborhood of €232 billion before year's end. If the estimate holds, this would be a 16 percent increase over the €200 billion raked by e-tailers during 2011, and is naturally assumed to come at the expense of traditional brick and mortar outfits, whose growth is projected to increase by a mere 1.8 percent.

The data gathered also suggest there's significant room for expansion, however, as online spending accounted for just 7.8 percent of all EU retail sales in 2011, with the UK, Germany and France being responsible for a whopping 71 percent of that tally. The 16 percent projected growth is a slight decline from 2011, which saw EU online spending grow by 18 percent -- although, Europe's growing habit for click-and-ship continues to outpace the US, which grew by only 12.8 percent in 2011. Now, since you've crammed all these numbers, why not check the funny pages?

[Shopping button via Shutterstock]

EU online spending estimated to grow 16 percent, reach ?232 billion in 2012 originally appeared on Engadget on Fri, 20 Jan 2012 21:45:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/01/20/eu-online-spending-to-reach-232-billion/

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Meet the super super PAC (Politico)

Super PACs are just so 2011.

Meet the next big thing in U.S. politics: the super super PAC.

Continue Reading

South Carolina Primary Live Coverage

These nascent groups can not only raise mega cash to promote candidates, but give money to candidates? campaigns ? a kind of political power and intimacy today?s super PACs alone can?t achieve.

Here?s how it works: under new federal rules, a traditional PAC and super PAC may operate under one roof. These hybrid operations can raise and spend unlimited amounts of cash to promote or oppose candidates, as any super PAC can, while simultaneously giving limited amounts of money directly to campaigns and committees, like a traditional political action committee.

Already, 11 of these hybrids have emerged, representing a range of political ideologies and purposes. They foreshadow even further tumult within the nation?s campaign finance system as the two-year anniversary of the seminal Citizens United v. Federal Election Commission decision arrives Saturday.

Several operatives involved with them predict the popularity of special interest hybrid PACs will explode during the next year as more organizations become aware of them and realize their benefits.

?Any PAC that doesn?t become a hybrid PAC is run by idiots. The default is going to be hybrid PACs,? said Dan Backer, the principal attorney at DB Capitol Strategies who successfully argued last year?s Carey v. Federal Election Commission case, the decision in which legalized hybrid PACs for those not tied to corporations and unions.

?It?d be ludicrous to limit your ability when you have this right,? he said. ?My thought is that we?ll never say ?super PAC? again in 10, maybe five years.?

PACs connected to corporations and unions, meanwhile, could soon win the same right, thanks to a case also initiated by Backer and pending before the Federal Election Commission. It?s expected to be settled by late winter.

Two major super PACs, both of which have poured millions of dollars into this year?s presidential campaign, confirm to POLITICO they?re considering morphing into hybrid PACs.

?If Newt Gingrich gets the nomination, we would want a very strong ticket up and down the line, and this would definitely help in that regard, giving us the ability to donate direct to candidates,? said Rick Tyler, an official at pro-Gingrich super PAC Winning Our Future, which to date has spent several million dollars promoting the House speaker or attacking his opponents. ?We?re not going to leave any weapon in the the arsenal.?

Said Abe Niederhauser, treasurer of the pro-Ron Paul Endorse Liberty super PAC: ?It seems like a big advantage. I?d be interested in learning more about it. We might want to do it.?

For PACs that have already gone hybrid ? they range from the Conservative Action Fund to the Gay and Lesbian Victory Fund ? the advantages are notable and immediate, several officials said.

One likened it to the difference between paying high home utility bills issued by several different companies versus paying one bill from single provider who bundles services together for a lower overall rate.

?It really makes it a lot easier to organize your efforts and fundraise. You?re looking at a 30, 40, 50 percent savings on overhead costs and administration alone,? said Dave Mason, a two-time FEC chairman who helped create PURO PAC, a hybrid formed last month to advocate for the premium cigar industry and support candidates who oppose federal cigar regulations. ?You can put that savings into politics, like ads or contributions. And for traditional PACs, it?s going to contribute to pushing their activity in the direction of more independent expenditures ? and I?m not saying whether that?s good or bad.?

Source: http://us.rd.yahoo.com/dailynews/rss/politics/*http%3A//us.rd.yahoo.com/dailynews/external/politico_rss/rss_politico_mostpop/http___www_politico_com_news_stories0112_71763_html/44256069/SIG=11megi108/*http%3A//www.politico.com/news/stories/0112/71763.html

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Sunday, January 22, 2012

Minn. bear delivers at least 2 cubs on Internet

(AP) ? A 3-year-old bear in Minnesota has given birth to two cubs before an Internet audience.

Lynn Rogers of the Wildlife Research Institute, affiliated with North American Bear Center, said in a news release that Jewel gave birth in a den near Ely to the first cub at 7:22 a.m. Sunday, and a second at 8:40.

It's not the first time Rogers and his colleagues have monitored hibernating pregnant black bears.

In 2010, they recorded the birth of a bear named Hope in 2010. A Hunter killed Hope last year.

Jewel is the younger sister of Hope's mother, Lily.

Lily also gave birth last year to two cubs named Faith and Jason.

___

Online:

North American Bear Center: http://www.bear.org

___

Information from: Duluth News Tribune, http://www.duluthsuperior.com

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-01-22-US-Internet-Bear-Sister/id-235fdb6533214241a5273199a71fc42b

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Fiery debate tops bizarre GOP campaign day in SC (AP)

NORTH CHARLESTON, S.C. ? The race for the Republican presidential nomination took a turn toward the South Carolina surreal Thursday as Rick Perry dropped out, Newt Gingrich faced stunning allegations from an ex-wife and Mitt Romney struggled to maintain a shaky front-runner's standing.

An aggressive evening debate capped the bewildering day.

Former Sen. Rick Santorum played aggressor for much of the night, trying to inject himself into what seemed increasingly like a two-way race with little more than a day remaining until the South Carolina polls open on Saturday. He accused Gingrich and Romney of "playing footsies with the left" when it came to health care. Both men rejected the allegations.

The debate began a few hours after first word that Romney had been stripped of his Iowa caucus victory, only to be stung a few hours later by Perry's withdrawal and endorsement of Gingrich.

Gingrich, in turn, was accused by an ex-wife of seeking an open marriage so he could keep his mistress.

"Newt's not perfect, but who among us is," said Perry, abruptly quitting the race just before the first-in-the-South primary.

His decision to end a once-promising candidacy left Romney, Gingrich, Santorum and Texas Rep. Ron Paul the remaining contenders in the race to pick a Republican to challenge Democratic President Barack Obama this fall.

Nine hours after Perry exited one stage, the four remaining contenders walked onto another for a final pre-primary debate.

Gingrich angrily denounced the news media for putting his ex-wife front and center in the final days of the race. "Let me be clear, the story is false," he said. Santorum, Romney and Paul steered well clear of the controversy. "Let's get onto the real issues, that's all I've got to say," said Romney, although he pointed out that he and his wife, Ann, have been married for 42 years.

The audience gave Gingrich a standing ovation when he assailed the media, a reaction he can only hope is reflected in voter sentiment on Saturday.

All four remaining GOP candidates lustily attacked Obama, while Santorum in particular sought to raise his own profile.

Introduced to the audience at the outset, he mentioned his change of fortunes in Iowa, where an evident eight-vote defeat in caucuses on Jan 3 was belated transformed into a 34-vote advantage ? though the Iowa Republican Party did not declare a winner.

Santorum jabbed at both Gingrich and Romney, but seemed to focus more attention on the former. If Gingrich is the party nominee, he said, "you sort of have that worrisome moment that something's going to pop. And we can't afford that in a nominee."

In a reflection of the complex political dynamics of the race, first Gingrich and then Santorum challenged Romney over his well-documented switch of position on abortion. Once a supporter of a woman's life to choose, he now says he is "pro-life."

Gingrich didn't exactly question Romney's change in position, but he didn't embrace it, either, saying, "He had an experience in a lab and became pro-life."

Romney bristled. "I'm not questioned on character or integrity very often. I don't feel like standing here for that."

Recent polls, coupled with Perry's endorsement, suggested Gingrich was the candidate with the momentum and Romney the one struggling to validate his standing as front-runner. Whatever else the impact, the day's events reduced the number of contenders vying to emerge as Romney's principal conservative alternative.

The former Massachusetts governor had other challenges in a state where unemployment approaches 10 percent. He adamantly refused to explain why some of his millions were invested in the Cayman Islands, how much was there or whether any other funds were held offshore.

Under pressure from his rivals to release his income tax returns before the weekend ? a demand first made by Perry in a debate on Monday ? he told reporters it wouldn't happen. "You'll hear more about that. April," he said, a position he renewed during the debate to jeers from the audience.

Gingrich pursued an approach Perry used in the earlier debate.

"If there's anything that's in there that's going to help us lose the election, we should know before the election. If there's not, why not release it?" he said.

Gingrich released his own tax return during the day, reporting that he paid the IRS $613,517 in taxes on more than $3.1 million in income. He also donated about 2 percent of his income to charity.

His effective tax rate, roughly 31.6 percent of his adjusted income, was about double what Romney told reporters earlier this week he had paid.

Gingrich grappled with problems of a different, possibly even more crippling sort in a state where more than half the Republican electorate is evangelical.

In an interview scheduled to air on ABC News, Marianne Gingrich said her ex-husband had wanted an "open marriage" so he could have both a wife and a mistress. She said Gingrich conducted an affair with Callista Bistek ? his current wife ? "in my bedroom in our apartment in Washington" while she was elsewhere.

"He was asking to have an open marriage and I refused. That is not a marriage," she said in excerpts released by the network in advance of the program.

He said his two daughters from the first of his three marriages ? the ex-wife making the accusations was the second of three ? had sent a letter to ABC "complaining about this as tawdry and inappropriate."

In fact, the letter made no such accusations. Instead, Kathy Lubbers and Jackie Cushman wrote ABC that anyone who has endured a failed marriage "understands it is a personal tragedy filled with regrets, and sometimes differing memories of events."

Those weren't the only political events in the run-up to the Saturday primary. Television commercials for the remaining candidates and their allies ran virtually without letup, generally designed to diminish each other's support.

According to information made available to The Associated Press, targeted viewers in most regions of the state were watching an average of about six commercials a day paid for by Romney's campaign and Restore Our Future, a group supporting him. Gingrich, Paul, Santorum and their backers raised the total higher.

Santorum ran commercials likening Romney to Obama; Gingrich's cast the former speaker as the only candidate who could defeat the president this fall. In a sign of the shifting campaign, Restore Our Future stopped attacking Santorum so it could concentrate its fire on Gingrich.

Santorum, whose fortunes have ebbed since what appeared to be a narrow loss in Iowa, pronounced himself the winner there after all when state party officials in Des Moines announced he had finished 34 votes ahead of Romney instead of eight behind.

"There have been two contests. We won one," he said, and he proceeded to ridicule Romney and Gingrich as weak challengers to Obama. "How can you differentiate ourselves on the major issues of the day if we nominate tweedledum and tweedledee instead of someone who stood up and said, `No'?" he said to one audience, referring to his opposition to a requirement to purchase health care coverage.

Iowa Republican chairman Matt Strawn said the party would not name an official winner because the results were so close and some votes couldn't be counted. Results from eight of the state's 1,774 precincts were not certified to the state party by Wednesday's 5 p.m. deadline.

It was Strawn who had stepped before a microphone shortly before 2 a.m. in Des Moines on Jan. 4 to declare Romney the victor.

That announcement propelled the former Massachusetts governor into New Hampshire, where he breezed to victory in the opening primary of the campaign a week later.

He arrived in South Carolina the following day, front-runner then for sure, now more shakily so.

Perry's withdrawal mimicked one earlier in the week by former Utah Gov. Jon Huntsman in that they both quit a few hours before a debate.

The similarities ended there, though. Huntsman endorsed Romney.

Perry had other thoughts, calling Gingrich a "conservative visionary who can transform our country."

Echoing words Huntsman said of Romney, Perry said he and Gingrich had their differences.

And in saying the former speaker was not perfect, he sought to provide political cover of a type that might reassure South Carolina voters for whom religious values are important.

"The fact is, there is forgiveness for those who seek God and I believe in the power of redemption, for it is a central tenet of my own Christian faith," Perry said.

His decision to withdraw set off a scramble among the remaining contenders for the allegiance of his supporters and donors, both in the state and nationally.

State Rep. Chip Limehouse of Charleston said he was expecting to speak by phone with both Romney and Gingrich later in the day before making up his mind.

"I'm looking and I really do think tonight's debate will determine the next president of the United States. That's how important it is," Peeler said.

Perry's exit marked the end of a campaign that began with soaring expectations but quickly faded. He shot to the head of the public opinion polls when he announced his candidacy last summer, but a string of poor debate performances soon led to a decline in support.

His defining moment came at one debate when he unaccountably could not recall the third of three federal agencies he has promised to abolish. He joked about it afterward but never recovered from the fumble.

In his farewell appearance as a candidate, he said he was bowing out of the 2012 campaign, seemingly a hint he would run again in four years if Republicans fail to win the White House this time.

An aide, Ray Sullivan was more explicit, telling reporters Perry hasn't ruled out running for governor again or for the White House in 2016 if Obama is re-elected.

___

Associated Press writers Thomas Beaumont, Beth Fouhy, Philip Elliott, Kasie Hunt and Shannon McCaffrey in South Carolina contributed to this story.

Source: http://us.rd.yahoo.com/dailynews/rss/gop/*http%3A//news.yahoo.com/s/ap/20120120/ap_on_el_ge/us_gop_campaign

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Mariah Carey: Jeweler Joan Boyce Is Not My Mother! (omg!)

Mariah Carey: Jeweler Joan Boyce Is Not My Mother!

Mariah Carey may be mom to 8-month-old twins Moroccan and Monroe, but when it comes to her own mother, she's not down for any baby mama drama.

PHOTOS: Moroccan, Monroe and more of 2011's babies of the year

On January 12, Carey, whose husband, Nick Cannon, is currently recovering from minor kidney failure, hit up the store of famed jeweler and longtime friend, Joan Boyce. Soon after, some outlets began referring to Boyce's boutique as "Mariah's parents' jewelry store."

PHOTOS: Mariah and Nick's love story

Shutting down those false speculations, both Boyce and Carey took to their twitter accounts to sound off.

"@MariahCarey M, congrats on BET Honors! Did you see they called me your mom again? It's so silly! You only have one mom and that's Pat Carey," Boyce tweeted at the singer on Friday.

"@joanboycehsn You'd think after she sang the duet with me last year & performed on my ABC Special in front of millions, people would get it!" the singer responded.

"I was extremely pregnant but here's a link to our moment together on stage 4 anyone who didn't see it. That's my momma!" Carey added, along with the video of her and her mom singing.

PHOTOS: Star moms and their fave Christmas photos

Pat, who's pictured with Mariah in the photo to the left, also appeared in a video for Mimi's holiday album, Merry Christmas II You in 2010.

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Mariah Carey: Jeweler Joan Boyce Is Not My Mother!

Source: http://us.rd.yahoo.com/dailynews/rss/entertainment/*http%3A//us.rd.yahoo.com/dailynews/external/omg_rss/rss_omg_en/news_mariah_carey_jeweler_joan_boyce_not_mother194350392/44256767/*http%3A//omg.yahoo.com/news/mariah-carey-jeweler-joan-boyce-not-mother-194350392.html

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Saturday, January 21, 2012

Grapefruit-Sized "Goal Balls" Aim to Clear Indonesian Train Roofs of Ruffians [Transportation]

Need to keep the riff-raff off the roof of your shiny new commuter train? Do what Indonesia's state railway did and just sweep the little bastards off with a broom made of suspended concrete balls. Remember to duck. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/hAup1eKxfvo/grapefruit+sized-goal-balls-aim-to-clear-indonesian-train-roofs-of-ruffians

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Genes May Give Clues to Severe Form of Lupus (HealthDay)

WEDNESDAY, Jan. 18 (HealthDay News) -- Researchers have identified a DNA sequence that appears to speed up the progression of lupus, an autoimmune disease in which the body's immune system attacks healthy tissues.

"Enhancers" are DNA sequences that accelerate the activation of neighboring genes, according to Italian researchers. In the case of lupus, researchers identified a particular DNA sequence, called HS1.2, which may play a role in the most severe cases of the disease, which can cause joint pain, fever, skin rashes, hair loss and anemia.

The study's authors explained that HS1.2 leads to increased activation of the "transcription factor NF-KB" (a molecule that "reads" the genes to make them work). As a result, this accelerator boosts the production of antibodies that attack the tissues, and increases the aggressiveness of the disease.

The discovery of the accelerator could lead to more effective treatments for lupus, such as medications that "turn off" the accelerator, the study authors said.

The study appears in the Annals of the Rheumatic Diseases.

"Our results suggest that new drugs that turn off the enhancer HS1.2, or inhibit its effect on NF-KB, can stop the disease without the need for immunosuppressive drugs or other therapies with many side effects," the study's leader, Gianfranco Ferraccioli of the Catholic University of Sacred Heart in Rome, said in a university news release. "Moreover, the discovery of the role of this enhancer allows us to better classify patients and formulate a precise prognosis for each one moving toward more personalized care."

Treatments for lupus include cortisone, antimalarial drugs, immunosuppressants and biologic drugs.

HS1.2 also plays a role in other autoimmune diseases such as rheumatoid arthritis, and may increase susceptibility to autoimmune diseases, according to the news release.

More information

The U.S. Department of Health and Human Services Office on Women's Health has more about autoimmune diseases.

Source: http://us.rd.yahoo.com/dailynews/rss/science/*http%3A//news.yahoo.com/s/hsn/20120119/hl_hsn/genesmaygivecluestosevereformoflupus

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